Statins and CKD; Farxiga’s Limited Symptom Improvement; Stop Wasted TNKase

Derick Alison
Derick Alison
3 Min Read

The prevalence of lower extremity artery disease was an estimated 9.7% around the world, reaching a high of 14.5% in South-Central Asia. (European Journal of Preventive Cardiology)

Removal of race stratification did not improve the performance of the pooled cohort risk equations in the prospective REGARDS cohort. (JAMA Cardiology)

Older veterans with stage 3-4 chronic kidney disease and no history of atherosclerotic cardiovascular disease had lower odds of poor clinical events if they started statin therapy. (JAMA Network Open)

A woman diagnosed with severe vasospastic angina was able to get pregnant and give birth without angina attacks after initiating diltiazem therapy. (JACC: Case Reports)

The SGLT2 inhibitor dapagliflozin (Farxiga) showed that its improvement of certain symptoms may be limited to heart failure patients with reduced ejection fraction in the DETERMINE trials. (Circulation)

For patients admitted to home hospital for heart failure, a retrospective analysis showed no unexpected deaths and the most common reason for escalation was progressive renal dysfunction. (Circulation: Cardiovascular Quality and Outcomes)

Across countries, spouses in the same household often share concordant hypertension diagnoses. (Journal of the American Heart Association)

Getinge’s Cardiohelp Emergency Drive is under class I recall due to an issue with the hand crank getting stuck, the FDA alerted.

Given that tenecteplase is only available in 50-mg vials, it is feasible to thaw previously frozen half-vials for treating stroke in order to reduce waste, one hospital found. (Stroke)

COVID pandemic waves were not accompanied by malignant ventricular arrhythmias, according to records from the Midi-Pyrénées area of France. (EP Europace)

Warfarin was associated with fewer thromboembolic events after surgical aortic valve replacement with bioprosthetic valves, albeit at the cost of more major bleeding. (Mayo Clinic Proceedings)

Mitral annular disjunction makes a difference in outcomes after mitral transcatheter edge-to-edge repair, one high-volume center found. (JACC: Cardiovascular Interventions)

A soundwave-sensitive ink was developed to quickly harden into a desired 3D structure in deep tissues with high spatial precision, with potential applications in left atrial appendage occlusion and heart valve repair. (Science)

Harlan Krumholz, MD, SM, of Yale School of Medicine, was named the new editor-in-chief of the Journal of the American College of Cardiology.

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    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow

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