Ketamine and Chronic Pain; Ivermectin Lawsuit and Public Health; JN.1 Keeps Growing

Derick Alison
Derick Alison
4 Min Read

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CNN looked at how chronic pain patients found relief with ketamine.

Two Colorado paramedics were convicted for giving a fatal overdose of ketamine to sedate Elijah McClain in 2019. (AP)

If the legal case about the FDA’s public statements on ivermectin and COVID-19 prevails, the agency’s ability to support evidence-based medicine may be undermined, a law scholar said. (New England Journal of Medicine)

U.S. abortion rulings and anti-LGBTQ+ laws influenced Canada’s decision to alert its citizens about travel risks last summer, Politico reported.

Meanwhile, large fentanyl labs in Canada may pose a new threat for the U.S. opioid crisis. (Washington Post)

COVID variant JN.1 continues to be the fastest-growing strain in the U.S. and accounts for 44% of cases, according to new CDC estimates. Here are its symptoms. (USA Today)

The FDA issued its final guidance document about direct-to-consumer prescription drug ads.

About 1 million Corewell Health patients in Michigan had personal and medical information exposed in a second data breach. (WXYZ)

NIH Director Monica Bertagnolli, MD, discussed drug patents, gain-of-function research, and overall trust in science in a New York Times interview.

About 1,800 Georgians have enrolled in a new Medicaid work requirement program in its 4 months. The state expected 31,000 people to sign up in the first year. (Politico)

Cases of extensively antibiotic-resistant Shigella sonnei infections — mainly in men who have sex with men — rose dramatically in the U.K. in 2023, the government health security agency said.

Young children screened in 2020 and 2021 were more likely to have high social-emotional scores, suggesting pandemic-related variables may have contributed to developmental delay. (JAMA Pediatrics)

Bayer ended its losing streak by winning a trial in a suit brought by a California man who said he developed cancer from exposure to its Roundup weedkiller. (Reuters)

The FDA nixed full approval of sotorasib (Lumakras) based on CodeBreaK 200 trial results and will require an additional confirmatory study, Amgen said. The drug received accelerated approval for previously treated KRAS G12C-mutated non-small cell lung cancer in 2021.

The agency also rejected dasiglucagon to treat pediatric patients with congenital hyperinsulinism based on inspection findings at a third-party manufacturing facility, according to Zealand Pharma.

Legend Biotech disclosed in a securities filing that the FDA updated a boxed warning about secondary cancers following treatment with ciltacabtagene autoleucel (Carvykti).

And the agency placed a clinical hold on a trial of LN-145 TIL for non-small cell lung cancer after a patient death, Iovance Biotherapeutics said.

Owning a pet was associated with slower declines in verbal memory and verbal fluency in older adults who lived alone, but not in those who lived with others. (JAMA Network Open)

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) advocate and #MEAction cofounder Beth Mazur died after a 15-year battle with ME.

A woman born with a double uterus delivered two babies from two uteri on two separate days. (CNN)

Former NFL player Mike Williams died from bacterial sepsis traced to a dental infection, according to a medical examiner’s report. Williams died in September at age 36. (AP)

  • Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more. Follow

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